February 25, 2010

Networks of actin filaments can provide force within a cell to generate movement, but the mechanism of how this occurs isn’t completely understood. A group recently created a computer model to simulate and predict motility caused by actin polymerization, and tested new predictions experimentally. The figure above shows how an actin network uniformly coating a bead will break its symmetry to result in movement of the bead (top). The computer simulation (middle) and a 3D view of the simulation (bottom) are also shown.


Mark J. Dayel, Orkun Akin, Mark Landeryou, Viviana Risca, Alex Mogilner, R. Dyche Mullins. Article found here.

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