April 15, 2010

The pancreas is made of several different types of cells, and these different types are all derived from the same set of progenitor cells during development. A recent paper investigated the role of a protein named Sel1 in the development of the pancreas, and reported that Sel1 is important for the growth and differentiation of the progenitor cells. Image is of early pancreas cells in the mouse, showing Sel1 (red) and Sox9 (green), used as a marker for pancreatic progenitor cells.

Reference: Shuai Li, Adam B Francisco, Robert J Munroe, John C Schimenti and Qiaoming Long. Authors’ BMC Developmental Biology paper can be found here.

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