It’s true that yeast isn’t considered the most photogenic organism around because of their tiny size, but I shudder to think how far behind we’d all be if it weren’t for the amazing discoveries made using yeast. Today, please enjoy these stunning images of fission yeast from a paper describing actin polymerization during endocytosis.
Endocytosis is the process during which a cell takes in material from the outside. Membrane-bound vesicles form within the cell to transport material to its final destination. Like most things dynamic in a cell, actin plays a very important role. In yeast, actin patches form at sites of endocytosis to help in membrane invagination and scission, key processes that result in the formation of a vesicle. A recent paper found that a protein called dip1p is a crucial switch to initiate the formation of actin patches at sites of endocytosis in fission yeast. Images above show a reduction in the number of actin patches in yeast without dip1p (right), compared to wild-type yeast (left).
Roshni Basu, & Fred Chang (2011). Characterization of Dip1p Reveals a Switch in Arp2/3-Dependent Actin Assembly for Fission Yeast Endocytosis Current Biology, 21 (11), 905-916 : doi:10.1016/j.cub.2011.04.047
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